Positive results from a number of studies on the effectiveness of furin inhibitors in mouse models have been published, including the effectiveness of treatment of murine pulmonary fibrosis induced by bleomycin [241], acute lung injury in a mouse model of Pseudomonas Aeruginosa infection [243], colorectal cancer [246], vascular remodeling and coronary atherosclerosis [70], epilepsy [246], and the regulation of learning and memory [155]. The gene discussed is FURIN; the disease is epilepsy.