IVL and acquired polycythemia vera: Concentrations of IVL, hBD-2 and the relative expression of hBD-2 mRNA and IVL mRNA were the highest in patients with PV (the average results demonstrated an approximately 1.6 and 4-fold increase in IVL mRNA and hBD-2 mRNA, respectively) and the lowest in C (near 0 for hBD-2 mRNA) (Figure 1a–d).