In a subsequent study, to further characterize the downstream CD147 signaling pathway/network, we also extended our analysis on the expression and function of two partner molecules, MCT1 and MCT4, in hematopoietic progenitor cells, in different leukemia cell lines, and in primary leukemic blasts from AML patients [15,42]. The gene discussed is SLC16A1; the disease is acute myeloid leukemia.