CD4 and chronic kidney disease: Regarding kidney function markers, eGFR (CKD-EPI) was directly associated with total lymphocytes count (r = 0.388, p = 0.009), T-cell counts (r = 0.328, p = 0.03) and CD4+ T-cells (r = 0.495, p = 0.001) in CKD patients (Appendix A, Table A1 and Table A2).