To the best of our knowledge, our exploratory study is the first to indicate independent correlations between cellular components of the innate and acquired immune system and specifically classical CD14++ monocytes, intermediate CD14++CD16+ monocytes, CD4+ T-cells, CD8+ T-cells and NK cells with the novel strain-related echocardiographic indices of subclinical myocardial dysfunction in CKD patients and KTRs without established CVD. Here, CD4 is linked to chronic kidney disease.