Interestingly, IFNγ produced by activated CD8+ T cells inhibits the expression of SLC3A2 and Solute Carrier Family 7 Member 11 (SLC7A11), components of the cystine/glutamate antiporter system xc-, promoting lipid peroxidation and ferroptosis in tumor cells [36,37]. The gene discussed is IFNG; the disease is neoplasm.