Myh4 is associated with Retinitis pigmentosa 67, a subtype of known ciliopathy associated with ciliary kinase Nek2 [79] while mutations in Myh8 were found in a variant of Carney Complex [80], a hereditary disease associated with mutations in Prkar2b, a regulatory subunit of protein kinase A, a key regulator of Hh signaling [25,81]. This evidence concerns the gene PRKAR2B and Carney complex.