IDH1 and malignant glioma: Diffuse pediatric-type high-grade glioma H3-wildtype and IDH-wildtype (pHGG H3/IDH WT) is a diverse entity currently characterized by an absence of oncohistone alterations (i.e., H3.3/H3.1/H3.2 pK27M) and methylation of three groups (i.e., pHGG RTK1, pHGG RTK2, pHGG MYCN) [40].