The deletion of Nfkbiz in hepatocytes using the Alb-Cre driver facilitated the progression of nonalcoholic fatty liver disease (NAFLD) in a mouse model that was induced by feeding with a choline-deficient, L-amino acid-defined, high-fat diet (CDAHFD) [86]. The gene discussed is ALB; the disease is metabolic dysfunction-associated steatotic liver disease.