CSF3 and IgA glomerulonephritis: Moreover, a recent clinical case demonstrated that strong bone-marrow stimulation by granulocyte colony-stimulating factor (G-CSF) caused a highly active form of IgA nephropathy, diagnosed following immunofluorescence on a renal biopsy specimen that showed massive staining of the mesangium for IgA light chains, C3, and lambda [26].