Human expression data had 546 of the 724 DEGs, and using abs(log2FC) > 1 and FDR < 0.05, 118 of the 546 DEGs were referred to as the Akt-YAP1 Sox9 LKO (null) or AY signature and applied to the TCGA HCC (Figure 3C). The gene discussed is AKT1; the disease is hepatocellular carcinoma.