Basta-Kaim et al. [36] in a study of lipopolysaccharide-induced schizophrenia (LPS) showed that behavioral changes accompanied by HPA axis dysregulation are characterized by elevated basal corticosterone levels in both male and female Wistar rats, which is accompanied by reduced GR expression in the hippocampus. This evidence concerns the gene NR3C1 and schizophrenia.