CXCL12 and neoplasm: Within the most highly expressed chemokines in tumor tissues, we observed the largest decrease in the number of transcripts (indicated by the tumor/cell culture ratio) for CCL3 (and CCL3L3), CCL4 (and CCL4L1), CCL5, CXCL1, CXCL3, CXCL14, and CXCL12, whereas the smallest changes were observed for CX3CL1, CCL2, CXCL16, and CXCL11 (Figure 3c).