Wild-type ARID1A and ARID1B are located at the promoter of CD274 in OCCC cells (shown in the human OVCA429 and RMG1 cell lines, as well as mouse ovarian ID8-Defb29/Vegf cancer cells), although ARID1B was not able to influence the levels of CD274 in ARID1A knockout (KO) cells [160]. The gene discussed is ARID1B; the disease is cancer.