Their analysis of DMRs shows that certain genes (BAG1, BTG2, CHP1, KIFC1, MKL2, MTR, PEX11B, POLD2, S100A6, SNORD104, and SPG7) were hypermethylated in BC survivors, while training was able to revert these genes back to a hypomethylated signature [43]. The gene discussed is S100A6; the disease is breast cancer.