TSGA10 and cancer: Mesenchymal–epithelial transition: Given the close association between TSGA10 and centrosomes [47], the involvement of centrosomes in cellular polarity (as a feature of epithelial cells versus mesenchymal cells), and a reduction in invasion capabilities of cancer cells with TSGA10 overexpression, one may conclude that TSGA10 may serve as a running factor of the mesenchymal–epithelial transition (MET).