Interestingly, the combination CA72-4, IL-6, IL-8, and TNFα gave better AUC values of 0.97 (95% CI = 0.95–0.99), 0.98 (95% CI = 0.96–0.99) and 0.96 (95% CI = 0.94–0.98) to discriminate between AH and GC, and EGC and advanced GC, respectively [51]. The gene discussed is TNF; the disease is gastric cancer.