A panel of 9 aAbs against TAAs, including c-Myc, p16, HSPD1 (Heat Shock Protein Family D (Hsp60) Member 1), PTEN (Phosphatase and tensin homolog), p53, NPM1 (Nucleophosmin 1), ENO1 (Enolase 1), p62, and HCC1.4, was identified, and it could distinguish GC cases from H controls with an AUC of 0.857 (sensitivity: 71.5%; specificity: 71.3%). Here, PTEN is linked to gastric cancer.