In fact, the programmed cell death-1 ligand (PD-L1) gene is located on chromosome 9p24.1, and PD-L1 expression has been reported to be linked to 9 amplification both in SMM and in MM [42], suggesting that SMM patients carrying chromosome 9 amplification might be considered to be more similar to MM than to MGUS [43]. Here, CD274 is linked to Miyoshi myopathy.