In cases of sudden deaths connected to epilepsy, variants in SCN5A, TBX18, KIF6, NEB, GUF1, TLR4, TRPM2, and PLA2G6 are all associated with SUDEP [68,69], as well as genes associated with severe epilepsies such as SCN1A and DEPDC5 [70]. Here, TLR4 is linked to epilepsy.