Negative correlations were noted between EDSS and IL-27p28 in the whole MS cohort (R = −0.31, p < 0.001) and in the PMS group (R = −0.38, p < 0.001) and between EDSS and IL-10 in the RRMS group (R = −0.41, p < 0.001). The gene discussed is IL10; the disease is premenstrual tension.