More recently, a study by Luining et al. [16] on 1879 EAU high-risk PCa patients (mainly scanned with 18F-DCFPyL and 68Ga-PSMA-11) reported an overall scan positivity rate of 45%, with a 10% prevalence of locoregional disease and a 35% rate of distant metastatic involvement. The gene discussed is FOLH1; the disease is posterior cortical atrophy.