Indeed, in the study by Malaspina et al. [18] on 79 intermediate and high-risk PCa patients, pelvic nodal localizations were detected by PSMA-PET/CT and CT in 34.2% and 10.1% of patients, respectively, resulting in a patient-level sensitivity of 87% (95% CI: 71–95) vs. 37% (22–55). Here, FOLH1 is linked to posterior cortical atrophy.