In Ph/−/ B-ALL a German group reports 46% 5-year OS for all types of IKZF1 deletion with a trend to statistical significance, and 35% 5-year OS for loss of function (LOF) deletions with a significant impact [13], but a UK team found no statistically significant impact on EFS and OS [15]. Here, IKZF1 is linked to acute lymphoblastic leukemia.