APOB and familial hypercholesterolemia: Familial hypercholesterolemia (FH) stands as a genetic disorder caused by mutations in cholesterol metabolism genes, primarily low-density lipoprotein receptor gene (LDLR), and to a lesser extent, apolipoprotein B gene (APOB) and proprotein convertase subtilisin-kexin 9 gene (PCSK9) [1,2].