Anamnestically, it appeared that the subject was suffering from AIDS (acquired immunodeficiency syndrome) with a CD4/CD8 ratio of 0.18, obesity, dyslipidemia, diabetes mellitus, arterial hypertension, chronic ischemic heart disease, chronic obstructive pulmonary disease with chronic respiratory failure under oxygen therapy treatment, chronic renal failure and neurological disorders, mainly represented by personality disorder and epilepsy. The gene discussed is CD8A; the disease is AIDS.