The variants included three channelopathy-associated genes (RYR2, CACNA1C, and ANK2), three HCM- or DCM-associated genes (MYH7, LDB3, and PRKAG2), five ACM-related genes (PKP2, JUP, DSG2, DSP, and TMEM43), and two cardiac transcription factor genes (TBX5 and GATA4). The gene discussed is ANK2; the disease is familial dilated cardiomyopathy.