Finally, compared to hypertensive patients without excessive daytime sleepiness, hypertensive patients with excessive daytime sleepiness had higher body mass index, CRP levels, triglyceride levels, Epworth Sleepiness Scale scores, Beck Depression Inventory scores and Insomnia Severity Index scores whereas they had a younger age and a lower number of antihypertensive medications. The gene discussed is CRP; the disease is depressive symptom measurement.