ESR1 and hyperlipidemia: The research results indicate that compounds in AHT, such as quercetin, luteolin, kaempferol, and baicalein, might affect hyperlipidemia by targeting core targets such as TP53, PPARG, ESR1, AKT1, RELA, MAPK1, as well as by acting on the PI3K-Akt and MAPK signaling pathways.