This was achieved through the regulation of the phosphatidylinositide 3-kinases (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) signaling pathway and further activation of the p38 mitogen-activated protein kinase (P38) signaling pathway, thereby exhibiting potent anti-cancer properties [93]. This evidence concerns the gene AKT1 and cancer.