PLOD1 and Alzheimer disease: Two hours after intraperitoneal injection of a glucose solution (2 g/kg), we found that the numbers of c-Fos+cells in the DMH, VMH, ARH, TuN, and LH were identical among the young groups (Young-WT-Male, Young-WT-Female, Young-AD-Male, Young-AD-Female mice) (Fig. 5A).