HSPG2 and neoplasm: By exploring GTEx and TCGA ovarian cancer datasets with the TCGA TARGET GTEx study online platform (https://xenabrowser.net/), we compared the expression of genes encoding the putative HPV receptor molecules in normal ovarian tissues (n = 88), primary ovarian tumor (n = 418), and recurrent ovarian tumor (n = 8), and found that the expression of HPV receptor molecules such as SDC1, ITGA6, HSPG2, are significantly higher in primary and recurrent tumor tissues when compared to that in the normal control tissue (P < 0.0001) (Fig. EV2).