RPTOR and vasculitis: To investigate whether SMC-specific Raptor deletion impacts luminal myofibroblast formation, Myh11CreERT2xRaptorfl/flxR26eYFP mice (where raptor is deleted from eYFP + /SMCs) and Myh11CreERT2xRaptor+/+xR26eYFP controls (where raptor is intact) were administered tamoxifen to trigger recombination in SMC, and then injected with CAWs to induce vasculitis (Fig. 6B).