RBFOX1 and autism spectrum disorder: Finally, after stringent control for multiple comparisons across all brain regions, we find statistically significant sex differences in the phenotypic effects of a common variant mapping to RBFOX1 - a known risk gene for neuropsychiatric and neurodevelopmental disorders like Autism Spectrum Disorder (ASD) and schizophrenia which are more common in one sex compared to the other28,29.