Multivariable regression analysis showed that baseline eGFR, UACR, pre-meal glucose, 2hPPG, average SG and TIR were the significant independent variables that affected SDF-1 levels in all participants with type 1 diabetes and diabetic nephropathy on the MiniMed 780G (Table 6). Here, CXCL12 is linked to type 1 diabetes mellitus.