CXCL8 and ovarian carcinoma: In another study, senescent human peritoneal mesothelial cells were found to modulate the secretory profile of ovarian cancer cells, specifically augmenting the secretion of four key angiogenic factors: CXCL1, CXCL8, HGF and VEGF, resulting in an enhanced angiogenic potential of the vascular endothelium.110