SKAP1 and malignant colon neoplasm: In parallel, we also assessed the cytotoxicity of NK cells without co‐culturing with neutrophils and found that SKAP1 overexpression only slightly reduced NK‐92MI‐mediated cell lysis of HCT116 cells in the absence of neutrophils (Figure 7C), suggesting that SKAP1 confers resistance to cytotoxic NK cells in colon cancer cells mainly through neutrophils.