In a xenograft model of human HCT116 colon cancer cells, the occurrence of visible tumors was accelerated by SKAP1 overexpression, with 87.5% of mice (7/8) in the SKAP1‐overexpressing group (HCT116‐SKAP1ov) showing visible tumors 7 days after inoculation, whereas 62.5% of mice (5/8) in the control group (HCT116‐EV) still showed no tumors (Figure 2C). This evidence concerns the gene SKAP1 and colonic neoplasm.