It has since been established that SKAP1 acts as an adaptor coupling the T‐cell receptor with “inside‐out” signaling for integrin‐mediated T‐cell adhesion, which is needed for the optimal antigen‐dependent activation of T cells.[4] Its role in regulating T‐cell immunity has also been investigated under pathological conditions such as autoimmune diseases[5] and cancers. Here, SKAP1 is linked to cancer.