Besides classical hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC), combined and intermediate forms of liver cancer exist and can express stem-cell markers like nuclear cell adhesion molecule (NCAM-1/CD56), c-kit (CD117), or epithelial cell adhesion molecule (EpCAM) together with high proliferative activity. This evidence concerns the gene NCAM1 and cholangiocarcinoma.