The risk prediction index predicted reasonable accuracy for NAT efficiency when using the three bacteria (AUC, 0.838; 95% CI, 0.743–0.933), which had better predictive efficiency than tumor size (AUC, 0.53; 95% CI, 0.404–0.656) and tumor stage (AUC, 0.65; 95% CI, 0.52–0.78). The gene discussed is BRD2; the disease is neoplasm.