Another study demonstrated that IGF2BP2 is recruited by m6A modified lncRNA PCAT6 (Prostate Cancer Associated Transcript 6) to interact with IGF1R (Insulin-Like Growth Factor I Receptor) mRNA, resulting in its stabilization and the promotion of PCa bone metastasis (Lang et al., 2021) (Figure 4). Here, IGF1R is linked to posterior cortical atrophy.