TUBB3 is a microtubule protein with important roles in chromosome segregation during mitosis, which was shown to be overexpressed in some cancers in a cell-cycle dependent manner, its overexpression leading to resistance to taxane derivates (Shibazaki et al., 2012), advanced tumor stage, and HER2 amplification in patient cohorts (Lebok et al., 2016). Here, TUBB3 is linked to cancer.