We and others have previously reported that CXCL10/CXCR3 signaling plays critical roles in melanoma tumor cell motility and metastases to the bone (Lee JH et al. 2012), lung (Wightman et al. 2015), and brain (Doron et al. 2019), accompanied with elevated CXCL10 levels in a mouse model of spontaneous melanoma metastasis. The gene discussed is CXCR3; the disease is neoplasm.