To investigate whether host-expressing CXC10 is essential for melanoma tumor growth, B16-FL cells (B16F10 murine melanoma cells stably expressing firefly luciferase) were subcutaneously implanted into wild-type (WT) and Cxcl10-/- syngeneic C57BL/6 mice. This evidence concerns the gene CXCL10 and melanoma.