MAPT and major depressive disorder: Search terms included “CJD” or “Creutzfeldt-Jakob disease” with three common psychiatric diagnoses, “Depression,” “Psychosis,” and “Mania.” Positive EEG, MRI, PET, and CSF (including protein 14-3-3 and tau) findings for CJD were found in 66.7, 81.1, 50, and 72.7% of cases, respectively.