Beyond axonogenesis in the tumor microenvironment, neurogenesis can also be observed: doublecortin-expressing neural progenitor cells metastasized from the CNS to prostate cancer, where they generated new adrenergic neurons to initiate neurogenesis (Mauffrey et al., 2019), and their density is strongly associated with prostate cancer aggressiveness and recurrence. Here, DCX is linked to neoplasm.