Furthermore, the AG genotype at rs11042167 and the GT genotype at rs2071095 were positively correlated with the expression of LincRNA H19 and miR-675 (P < 0.001), supporting the potential of the H19/LincRNA H19/miR-675/MRP3-HOXA1-MMP16 axis as a new direction for targeted therapy in breast cancer. The gene discussed is H19; the disease is breast carcinoma.