RALA and chronic myelogenous leukemia, BCR-ABL1 positive: On the basis of constructing a mouse model that overexpressed RalA GTPase, Professor Fei Jia’s team used single-cell transcriptomic technology to detect the effect of RalA overexpression on the self-renewal of bone marrow hematopoietic stem/progenitor cells in normal mice, and provided a theoretical basis for the clinical use of RalA inhibitors in the treatment of CML (102).