NLRP3 and neoplasm: In triple-negative breast cancer (TNBC), the inhibition of MEG3 not only partially mitigated the stimulatory effect of DDP on the NLRP3/caspase-1/GSDMD-mediated pyroptosis pathways, but also counteracted DDP’s inhibitory effect on tumour growth and metastasis, highlighting new avenues for the development of innovative therapeutic approaches for TNBC (150).