PSPH and liver cancer: Conversely, PSPH and PSAT1 mRNA levels (Figure 6F-G) and protein levels (Figure 6H-I) were dramatically upregulated in TRIM71 and YAP5SA + TRIM71 mice liver tumor tissues compared to the control group, and inhibition of TRIM71 or CEBPA decreased cellular serine and glycine levels in HuH-7 and Hep3B liver cancer cells (Figure 6J).