Other primary immunodeficiencies, such as Dedicator Of Cytokinesis 8 (DOCK8) deficiency, Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) syndrome, and Epidermodysplasia Verruciformis are associated with HPV disease, implying that multiple mechanisms are involved in the control of HPV infection (11). Here, DOCK8 is linked to inborn error of immunity.