Other primary immunodeficiencies, such as Dedicator Of Cytokinesis 8 (DOCK8) deficiency, Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) syndrome, and Epidermodysplasia Verruciformis are associated with HPV disease, implying that multiple mechanisms are involved in the control of HPV infection (11). This evidence concerns the gene DOCK8 and WHIM syndrome.