In summary, it is imperative to elucidate the immunoregulatory pathways and expression patterns of B7-H4 in ovarian cancer, identify its receptor(s), investigate downstream mechanisms of B7-H4 with effector T cells and other APC surface receptors, examine its role within the ovarian cancer microenvironment, including potential variances across different histological subtypes. This evidence concerns the gene VTCN1 and ovarian carcinoma.