ALL 3 expressed surface proteins CD19, CD38, CD44, CD45RA, CD49d, CD95, and HLA-DR; had an incomplete diploid set of chromosomes, had an altered karyotype 45,XY,der(3),?i(9)(q10),der(9),-10,der(14),der(15); had an increased number of copies of the CDKN1A gene, and also had a decreased number of copies of the CDKN2C, PIK3CA, DCUN1D1, PTPRD, AKT3, CCND1, EEF1A2, NKX2-1, and NKX2-8 genes. This evidence concerns the gene PIK3CA and acute lymphoblastic leukemia.