On the other hand, for patients with elevated PRL levels at baseline, aripiprazole successfully reduced serum PRL levels and decreased the proportion of patients with abnormal PRL levels among those with acute episode of schizophrenia, regardless of whether or not their elevated PRL levels had been caused by prior systemic treatment with antipsychotics, which is consistent with results of some previous studies. The gene discussed is PRL; the disease is schizophrenia.