TLR4 and liver dysplastic nodule: Shunyu Lu et al. [11], in studying the improvement of DN by DMDD through the TLR4/MyD88/NF-κB pathway, found that DN was associated with inflammatory response, and the levels of IL-6 and TNF-α in DN mice were suppressed after intervention with DMDD, which proved that DMDD could effectively improve the inflammatory response in DN mice.